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A two-stage model of dendritic integration in CA1 pyramidal neurons (Katz et al. 2009)
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"... In a two-stage integration model, inputs contribute directly to dendritic spikes, and outputs from multiple branches sum in the axon. ... We used serial-section electron microscopy to reconstruct individual apical oblique dendritic branches of CA1 pyramidal neurons and observe a synapse distribution consistent with the two-stage integration model. Computational modeling suggests that the observed synapse distribution enhances the contribution of each dendritic branch to neuronal output."
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Hippocampus CA1 pyramidal GLU cell Show
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Neuron or other electrically excitable cell Show
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Katz Y, Menon V, Nicholson DA, Geinisman Y, Kath WL, Spruston N (2009) Show
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