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Data
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Selective control of cortical axonal spikes by a slowly inactivating K+ current (Shu et al. 2007)
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We discovered a low-threshold, slowly inactivating K+ current, containing Kv1.2 alpha subunits, in axon initial segment, playing a key role in the modulation of spike threshold and spike duration as well as
the spike timing in prefrontal cortex layer V pyramidal cell of ferrets and rats.
A kd.mod file implements this D current and put it in the axonal model: Neuron_Dcurrent.hoc. Run the model to see the gradual modulation effect over seconds on spike shape.
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Shu Y, Yu Y, Yang J, McCormick DA (2007) Show
Other
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tom.morse@yale.edu
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335
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