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Effect of trp-like current on APs during exposure to sinusoidal voltage (Chen et al. 2010)
V_trp [?]
"... Previous work showed that magnetic electrical field-induced antinoceptive action is mediated by activation of capsaicin-sensitive sensory afferents. In this study, a modified Hodgkin-Huxley model, in which TRP-like current (I-TRP) was incorporated, was implemented to predict the firing behavior of action potentials (APs), as the model neuron was exposed to sinusoidal changes in externally-applied voltage. ... Our simulation results suggest that modulation of TRP-like channels functionally expressed in small-diameter peripheral sensory neurons should be an important mechanism through which it can contribute to the firing pattern of APs."
  • Chen BS, Lo YC, Lius YC, Wu SN (2010) Show Other
  • Wu, Sheng-Nan [snwu at mail.ncku.edu.tw] Show Other
snwu@mail.ncku.edu.tw
I(trp)
Chen BS, Lo YC, Liu YC, Wu SN. Effects of transient receptor potential-like current on the firing pattern of action potentials in the Hodgkin-Huxley neuron during exposure to sinusoidal external voltage. Chinese Journal of Physiology 2010; 53(6):423-429.
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Revisions: 7
Last Time: 2/8/2011 11:51:23 AM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin