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Mechanisms of magnetic stimulation of central nervous system neurons (Pashut et al. 2011)
pashut2011 [445134]
Transcranial magnetic stimulation (TMS) is a widely applied tool for probing cognitive function in humans and is one of the best tools for clinical treatments and interfering with cognitive tasks. Surprisingly, while TMS has been commercially available for decades, the cellular mechanisms underlying magnetic stimulation remain unclear. Here we investigate these mechanisms using compartmental modeling. We generated a numerical scheme allowing simulation of the physiological response to magnetic stimulation of neurons with arbitrary morphologies and active properties. Computational experiments using this scheme suggested that TMS affects neurons in the central nervous system (CNS) primarily by somatic stimulation.
  • Neocortex L5/6 pyramidal GLU cell Show Other
  • Neuron or other electrically excitable cell Show Other
  • Pashut T, Wolfus S, Friedman A, Lavidor M, Bar-Gad I, Yeshurun Y, Korngreen A (2011) Show Other
  • Korngreen, Alon [alon.korngreen at gmail.com] Show Other
  • Pashut, Tamar [tamar.pashut at gmail.com] Show Other
alon.korngree@biu.ac.il
magnetic stimulation
Pashut, Tamar <tamar.pashut@gmail.com>
http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1002022
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