BrainPharm: Computational model - Cancelling redundant input in ELL pyramidal cells (Bol et al. 2011)

Computational model

Data

Name

Cancelling redundant input in ELL pyramidal cells (Bol et al. 2011)

Submitter name

Pipeline ID

Model File

ELLnoisecancelmodel [?]

Notes

The paper investigates the property of the electrosensory lateral line lobe (ELL) of the brain of weakly electric fish to cancel predictable stimuli. Electroreceptors on the skin encode all signals in their firing activity, but superficial pyramidal (SP) cells in the ELL that receive this feedforward input do not respond to constant sinusoidal signals. This cancellation putatively occurs using a network of feedback delay lines and burst-induced synaptic plasticity between the delay lines and the SP cell that learns to cancel the redundant input. Biologically, the delay lines are parallel fibres from cerebellar-like granule cells in the eminentia granularis posterior. A model of this network (e.g. electroreceptors, SP cells, delay lines and burst-induced plasticity) was constructed to test whether the current knowledge of how the network operates is sufficient to cancel redundant stimuli.

Model Neurons

More Cells

ELL pyramidal cell Show Other

Model Currents

Model Receptors

Model Type

Realistic Network Show Other
Neuron or other electrically excitable cell Show Other

Model Concept

Dendritic Action Potentials Show Other
Bursting Show Other
Active Dendrites Show Other
Synaptic Plasticity Show Other
Long-term Synaptic Plasticity Show Other
Learning Show Other
Unsupervised Learning Show Other
STDP Show Other
Biofeedback Show Other
Noise Sensitivity Show Other

Simulator software

C or C++ program Show Other
MATLAB Show Other

Model papers

Bol K, Marsat G, Harvey-Girard E, Longtin A, Maler L (2011) Show Other

Gene

hg folder name (applicable when in ModelDB hg)

Region Organism

Cerebellum Show Other

Model ID Number

Gap Junctions

Implemented by

Bol, Kieran [kieran_bol at hotmail.com] Show Other

Public Submitter Email Address

kbol098@uottawa.ca

Other Neuron

Model Neurotransmitters

Other Receptor

Other Current

Other Neurotransmitter

Other Model Type

Other Concept

Other Simulator

Other Implementer

Bol, Kieran <kieran_bol@hotmail.com>

Alternative Version

Citation

Default File Notes

Other Gene

Simulation Platform ID

Has Model View

False

Component

RAM

Hide Auto-launch button

False

Run Protocols

ICG Channel Details

Species

Other categories referring to Cancelling redundant input in ELL pyramidal cells (Bol et al. 2011)

Revisions:	4
Last Time:	8/8/2011 11:03:57 AM
Reviewer:
Owner:	Tom Morse - MoldelDB admin