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Data
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Ion concentration dynamics as a mechanism for neuronal bursting (Barreto & Cressman 2011)
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"We describe a simple conductance-based model neuron that includes intra and
extracellular ion concentration dynamics and show that this model exhibits periodic
bursting. The bursting arises as the fast-spiking behavior of the neuron is modulated
by the slow oscillatory behavior in the ion concentration variables and vice versa. By
separating these time scales and studying the bifurcation structure of the neuron, we catalog
several qualitatively different bursting profiles that are strikingly similar to those seen in
experimental preparations. Our work suggests that ion concentration dynamics may play an
important role in modulating neuronal excitability in real biological systems."
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Neuron or other electrically excitable cell Show
Other
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ebarreto@gmu.edu
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Hodgkin-Huxley + ion concentration dynamics
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