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Effects of the membrane AHP on the Lateral Superior Olive (LSO) (Zhou & Colburn 2010)
This simulation study investigated how membrane afterhyperpolarization (AHP) influences spiking activity of neurons in the Lateral Superior Olive (LSO). The model incorporates a general integrate-and-fire spiking mechanism with a first-order adaptation channel. Simulations focus on differentiating the effects of GAHP, tauAHP, and input strength on (1) spike interval statistics, such as negative serial correlation and chopper onset, and (2) neural sensitivity to interaural level difference (ILD) of LSO neurons. The model simulated electrophysiological data collected in cat LSO (Tsuchitani and Johnson, 1985).
  • Lateral Superior Olive (LSO) cell Show Other
  • Abstract integrate-and-fire leaky neuron Show Other
  • Neuron or other electrically excitable cell Show Other
zhouyi@jhu.edu
Lateral Superior Olive (LSO) cell
Integrate-and-fire
Effects of membrane afterhyperpolarization on discharge interval statistics: A model study of responses of lateral superior olive neurons to ipsilateral and bilateral acoustic stimuli. J. Neurophysiol. 103: 2355-2371.
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Revisions: 15
Last Time: 10/18/2018 5:01:40 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin