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Inhibitory plasticity balances excitation and inhibition (Vogels et al. 2011)
"Cortical neurons receive balanced excitatory and inhibitory synaptic currents. Such a balance could be established and maintained in an experience-dependent manner by synaptic plasticity at inhibitory synapses. We show that this mechanism provides an explanation for the sparse firing patterns observed in response to natural stimuli and fits well with a recently observed interaction of excitatory and inhibitory receptive field plasticity. ... Our results suggest an essential role of inhibitory plasticity in the formation and maintenance of functional cortical circuitry."
  • Neuron or other electrically excitable cell Show Other
  • Vogels TP, Sprekeler H, Zenke F, Clopath C, Gerstner W (2011) Show Other
  • Zenke, Friedemann [friedemann.zenke at epfl.ch] Show Other
  • Vogels, Tim [tim.vogels at epfl.ch] Show Other
tom.morse@yale.edu
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Revisions: 8
Last Time: 7/28/2017 1:53:57 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin