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Hodgkin-Huxley model of persistent activity in PFC neurons (Winograd et al. 2008) (NEURON python)
The paper demonstrate a form of graded persistent activity activated by hyperpolarization. This phenomenon is modeled based on a slow calcium regulation of Ih, similar to that introduced earlier for thalamic neurons (see Destexhe et al., J Neurophysiol. 1996). The only difference is that the calcium signal is here provided by the high-threshold calcium current (instead of the low-threshold calcium current in thalamic neurons).
  • Winograd M, Destexhe A, Sanchez-Vives MV (2008) Show Other
  • Skolnick, Yosef [yskolnick at gmail.com] Show Other
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Revisions: 10
Last Time: 1/2/2015 10:30:15 PM
Reviewer: Robert A McDougal
Owner: Tom Morse - MoldelDB admin