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Half-center oscillator database of leech heart interneuron model (Doloc-Mihu & Calabrese 2011)
We have created a database (HCO-db) of instances of a half-center oscillator computational model [Hill et al., 2001] for analyzing how neuronal parameters influence network activity. We systematically explored the parameter space of about 10.4 million simulated HCO instances and corresponding isolated neuron model simulations obtained by varying a set of selected parameters (maximal conductance of intrinsic and synaptic currents) in all combinations using a brute-force approach. We classified these HCO instances by their activity characteristics into identifiable groups. We built an efficient relational database table (HCO-db) with the resulting instances characteristics.
  • Doloc-Mihu A, Calabrese RL (2011) Show Other
  • Doloc-Mihu, Anca [adolocm at emory.edu] Show Other
adolocm@emory.edu
MySQL (web link to model)
Doloc-Mihu, Anca [adolocm at emory.edu]
Doloc-Mihu A, Calabrese RL. (2011) A database of computational models of a half-center oscillator for analyzing how neuronal parameters influence network activity. J Biol Phys. 37(3):263-83. [PMID: 22654177]
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Revisions: 23
Last Time: 2/26/2019 10:22:46 AM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin