BrainPharm: Computational model - Hypocretin and Locus Coeruleus model neurons (Carter et al 2012)

Computational model

Data

Name

Hypocretin and Locus Coeruleus model neurons (Carter et al 2012)

Submitter name

Pipeline ID

Model File

CarterEtAl2012 [?]

Notes

Conductance based model of the hypocretin neurons (HCRT) and another one of the Locus Coeruleus one (LC). The HCRT drive the LCs via the HCRT receptor on the LCs. The LCs lead to the awakening of the mice if the number of spikes raises over 10 spikes in 10 seconds window.

Model Neurons

More Cells

Locus Coeruleus neuron Show Other

Model Currents

I Na,t Show Other
I T low threshold Show Other
I A Show Other
I K Show Other
I K,Ca Show Other
I Calcium Show Other

Model Receptors

Model Type

Axon Show Other
Channel/Receptor Show Other

Model Concept

Simulator software

C or C++ program Show Other

Model papers

Carter ME, Brill J, Bonnavion P, Huguenard JR, Huerta R, de Lecea L (2012) Show Other

Gene

hg folder name (applicable when in ModelDB hg)

Region Organism

Model ID Number

Gap Junctions

Implemented by

Huerta, Ramon [rhuerta at ucsd.edu] Show Other

Public Submitter Email Address

rhuerta@ucsd.edu

Other Neuron

Locus Coeruleus neuron

Model Neurotransmitters

Other Receptor

Other Current

Other Neurotransmitter

Other Model Type

Other Concept

Other Simulator

Other Implementer

Huerta, Ramon, <rhuerta@ucsd.edu>

Alternative Version

Citation

Matthew E. Carter, Julia Brill, Patricia Bonnavion, John R. Huguenard, Ramon Huerta, and Luis de Lecea, "Mechanism for Hypocretin-mediated sleep-to-wake transitions", PNAS 2012

Default File Notes

Other Gene

Simulation Platform ID

Has Model View

False

Component

RAM

Hide Auto-launch button

False

Run Protocols

ICG Channel Details

Species

Other categories referring to Hypocretin and Locus Coeruleus model neurons (Carter et al 2012)

Revisions:	5
Last Time:	9/26/2012 2:00:56 PM
Reviewer:	Tom Morse - MoldelDB admin
Owner:	Tom Morse - MoldelDB admin