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Composite spiking network/neural field model of Parkinsons (Kerr et al 2013)
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This code implements a composite model of Parkinson's disease (PD). The composite model consists of a leaky integrate-and-fire spiking neuronal network model being driven by output from a neural field model (instead of the more usual white noise drive). Three different sets of parameters were used for the field model: one with basal ganglia parameters based on data from healthy individuals, one based on data from individuals with PD, and one purely thalamocortical model. The aim of this model is to explore how the different dynamical patterns in each each of these field models affects the activity in the network model.
  • Neocortex M1 L2/6 pyramidal intratelencephalic GLU cell Show Other
  • Neocortex M1 L5B pyramidal pyramidal tract GLU cell Show Other
  • Neocortex fast spiking (FS) interneuron Show Other
  • Neocortex spiking low threshold (LTS) neuron Show Other
  • Kerr CC, Van Albada SJ, Neymotin SA, Chadderdon GL, Robinson PA, Lytton WW (2013) Show Other
  • Kerr, Cliff [cliffk at neurosim.downstate.edu] Show Other
cliffk@neurosim.downstate.edu
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Revisions: 15
Last Time: 7/3/2017 10:27:58 PM
Reviewer: System Administrator
Owner: Tom Morse - MoldelDB admin