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Using Strahler`s analysis to reduce realistic models (Marasco et al, 2013)
Building on our previous work (Marasco et al., (2012)), we present a general reduction method based on Strahler's analysis of neuron morphologies. We show that, without any fitting or tuning procedures, it is possible to map any morphologically and biophysically accurate neuron model into an equivalent reduced version. Using this method for Purkinje cells, we demonstrate how run times can be reduced up to 200-fold, while accurately taking into account the effects of arbitrarily located and activated synaptic inputs.
  • Marasco A, Limongiello A, Migliore M (2013) Show Other
  • Limongiello, Alessandro [alessandro.limongiello at unina.it] Show Other
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Revisions: 15
Last Time: 1/14/2015 2:44:50 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Michele Migliore