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Data
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Gating of steering signals through phasic modulation of reticulospinal neurons (Kozlov et al. 2014)
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" ... We use the lamprey as a model for investigating the role of this
phasic modulation of the reticulospinal activity, because the
brainstem–spinal cord networks are known down to the cellular level in
this phylogenetically oldest extant vertebrate.
We describe how the phasic modulation of reticulospinal activity from
the spinal CPG ensures reliable steering/turning commands without the
need for a very precise timing of on- or offset, by using a
biophysically detailed large-scale (19,600 model neurons and 646,800
synapses) computational model of the lamprey brainstem–spinal cord
network.
To verify that the simulated neural network can control body
movements, including turning, the spinal activity is fed to a
mechanical model of lamprey swimming.
..."
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Kozlov AK, Kardamakis AA, Hellgren Kotaleski J, Grillner S (2014) Show
Other
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Kozlov, Alexander [akozlov at nada.kth.se] Show
Other
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tom.morse@yale.edu
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