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Olfactory bulb juxtaglomerular models (Carey et al., 2015)
ModelDB [15023578]
" ...We investigated how OB circuits shape inhalation-driven dynamics in MCs using a modeling approach that was highly constrained by experimental results. First, we constructed models of canonical OB circuits that included mono- and disynaptic feedforward excitation, recurrent inhibition and feedforward inhibition of the MC. We then used experimental data to drive inputs to the models and to tune parameters; inputs were derived from sensory neuron responses during natural odorant sampling (sniffing) in awake rats, and model output was compared to recordings of MC responses to odorants sampled with the same sniff waveforms. This approach allowed us to identify OB circuit features underlying the temporal transformation of sensory inputs into inhalation-linked patterns of MC spike output. ..."
  • Olfactory bulb main mitral GLU cell Show Other
  • Olfactory receptor GLU cell Show Other
  • Olfactory bulb main interneuron periglomerular GABA cell Show Other
  • Olfactory bulb main interneuron granule MC GABA cell Show Other
  • Olfactory bulb main interneuron granule TC GABA cell Show Other
  • Carey RM, Sherwood WE, Shipley MT, Borisyuk A, Wachowiak M (2015) Show Other
ryanmcarey@gmail.com
Olfactory bulb external tufted cell
False
False
Other categories referring to Olfactory bulb juxtaglomerular models (Carey et al., 2015)
Revisions: 10
Last Time: 10/17/2018 4:14:28 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin