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Data
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PreBotzinger Complex inspiratory neuron with NaP and CAN currents (Park and Rubin 2013)
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We have built on earlier models to develop a single-compartment Hodgkin-Huxley type model incorporating NaP and CAN currents, both of which can play important roles in bursting of inspiratory neurons in the PreBotzinger Complex of the mammalian respiratory brain stem. The model tracks the evolution of membrane potential, related (in)activation variables, calcium concentration, and available fraction of IP3 channels. The model can produce several types of bursting, presented and analyzed from a dynamical systems perspective in our paper.
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Neuron or other electrically excitable cell Show
Other
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Rubin, Jonathan E [jonrubin at pitt.edu] Show
Other
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Park, Choongseok [cpark at ncat.edu] Show
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jonrubin@pitt.edu
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Park, Choongseok <cpark@ncat.edu>
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C. Park and J.E. Rubin, J. Comp. Neurosci., 34:345-366, 2013.
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