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Squid axon (Hodgkin, Huxley 1952) used in (Chen et al 2010) (R language)
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"... Previous work showed that magnetic electrical field-induced antinoceptive action is mediated by activation of capsaicin-sensitive sensory afferents. In this study, a modified Hodgkin-Huxley model, in which TRP-like current (I-TRP) was incorporated, was implemented to predict the firing behavior of action potentials (APs), as the model neuron was exposed to sinusoidal changes in externally-applied voltage. ... Our simulation results suggest that modulation of TRP-like channels functionally expressed in small-diameter peripheral sensory neurons should be an important mechanism through which it can contribute to the firing pattern of APs."
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snwu@mail.ncku.edu.tw
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1. Hopgkin AL, Huxley AF. A quantitative description of membrane current and its application to conduction and excitation in nverve. J Physiol 1952;117:500-44. 2. Chen BS, Lo YC, Liu YC, Wu SN. Effects of transient receptor-like current on firing pattern of actions potentials in the Hodgkin-Huxley neuron during exposure to sinusoidal external voltage. Chin J Physiol 2010;53:423-9.
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