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Neuron
  Data
Olfactory bulb main tufted middle GLU cell
18,280
 Neuronal Receptors (40)
  
SN Property present CF-Compartment Receptor Connect Note Publication facts
1 Yes Distal basal dendrite mGluR7 Possible
2 Yes Distal basal dendrite mGluR4 Possible
3 Yes Middle basal dendrite NMDA Paired recordings in slices showed excitatory transmission mediated solely by transmitter spillover between mitral cells. Dendritic glutamate release causes self-excitation via local activation of NMDA receptors, and generates NMDA receptor-mediated responses in neighbouring cells. It is suggested that this simultaneous activation of neighbouring cells by a diffuse action of glutamate provides a mechanism for synchronizing olfactory principal cells
4 Yes Middle basal dendrite mGluR4 Possible
5 Yes Middle basal dendrite mGluR1 Auto-activation from glutamate released by mitral cell secondary dendrites
6 Yes Proximal apical dendrite GabaB The kinetics of GABA currents were studied using flash photolysis of caged GABA
7 Yes Distal apical dendrite mGluR
8 Yes Middle basal dendrite GabaA Identification of subunit mRNAs
9 Yes Distal apical dendrite GabaB
10 Yes Soma GabaA The kinetics of GABA currents were studied using flash photolysis of caged GABA
11 Yes Distal apical dendrite Dopaminergic Receptor DA receptors in mitral cell dendrites implied by DA localization in PG dendrites presynaptic to mitral dendrites
12 Yes Distal apical dendrite AMPA Paired whole-cell recording revealed reciprocal excitatory connections between mitral cells. Pharmacological analysis suggested that it could be mediated by both AMPA and NMDA receptors
13 Yes Distal apical dendrite NMDA Paired whole-cell recording revealed reciprocal excitatory connections between mitral cells. Pharmacological analysis suggested that it could be mediated by both AMPA and NMDA receptors
14 Yes Distal apical dendrite GabaA Identification of subunit mRNAs
15 Yes Distal basal dendrite NMDA Paired recordings in slices showed excitatory transmission mediated solely by transmitter spillover between mitral cells. Dendritic glutamate release causes self-excitation via local activation of NMDA receptors, and generates NMDA receptor-mediated responses in neighbouring cells. It is suggested that this simultaneous activation of neighbouring cells by a diffuse action of glutamate provides a mechanism for synchronizing olfactory principal cells
16 Yes Distal basal dendrite mGluR1 Auto-activation from glutamate released by mitral cell secondary dendrites
17 Yes Middle basal dendrite mGluR6 Possible
18 Yes Proximal basal dendrite GabaA Identification of subunit mRNAs
19 Yes Proximal basal dendrite NMDA Paired recordings in slices showed excitatory transmission mediated solely by transmitter spillover between mitral cells. Dendritic glutamate release causes self-excitation via local activation of NMDA receptors, and generates NMDA receptor-mediated responses in neighbouring cells. It is suggested that this simultaneous activation of neighbouring cells by a diffuse action of glutamate provides a mechanism for synchronizing olfactory principal cells
20 Yes Proximal basal dendrite AMPA The pharmacology and kinetics of glutamate sensitivity of mitral cells was studied using flash photolysis in rats
21 Yes Proximal basal dendrite mGluR1 Auto-activation from glutamate released by mitral cell secondary dendrites
22 Yes Middle apical dendrite NMDA Paired recordings in slices showed excitatory transmission mediated solely by transmitter spillover between mitral cells. Dendritic glutamate release causes self-excitation via local activation of NMDA receptors, and generates NMDA receptor-mediated responses in neighbouring cells. It is suggested that this simultaneous activation of neighbouring cells by a diffuse action of glutamate provides a mechanism for synchronizing olfactory principal cells
23 Yes Proximal apical dendrite NMDA The pharmacology and kinetics of glutamate sensitivity of mitral cells was studied using flash photolysis in rats
24 Yes Soma NMDA In an immunocytochemical study in zebrafish all cells resulted in NMDA receptor mediated labelling
25 Yes Middle basal dendrite AMPA With a postembedding immunogold procedure, it has been found that these receptors do not appear to be concentrated in clusters on dendrites, suggesting that the presynaptic effects of glutamate are mediated by a small complement of extrasynaptic receptors
26 Yes Soma Kainate In an immunocytochemical study in zebrafish 60-70% of cells showed KA receptor mediated labelling
27 Yes Soma AMPA The pharmacology and kinetics of glutamate sensitivity of mitral cells was studied using flash photolysis in rats
28 Yes Soma GabaB
29 Yes Distal basal dendrite GabaA Identification of subunit mRNAs
30 Yes Proximal apical dendrite GabaA Identification of subunit mRNAs
31 Yes Soma mGluR1 Auto-activation from glutamate released by mitral cell soma
32 Yes Distal apical dendrite mGluR1 Auto-activation from glutamate released by mitral cell secondary dendrites
33 Yes Middle apical dendrite GabaA Identification of subunit mRNAs
34 Yes Distal basal dendrite AMPA With a postembedding immunogold procedure, it has been found that these receptors do not appear to be concentrated in clusters on dendrites, suggesting that the presynaptic effects of glutamate are mediated by a small complement of extrasynaptic receptors
35 Yes Distal basal dendrite mGluR6 Possible
36 Yes Middle basal dendrite mGluR7
37 Yes Middle apical dendrite Dopaminergic Receptor
38 Yes Proximal basal dendrite GabaB The kinetics of GABA currents were studied using flash photolysis of caged GABA
39 Yes Distal basal dendrite GabaB
40 Yes Middle basal dendrite GabaB
 Neuronal Currents (32)
  
SN Property present CF-Compartment Current Connect Note Publication facts
1 Yes Distal apical dendrite I Na,t By combining intracellular recordings and two-photon microscopy imaging of [Ca]i in rat it was shown that APs backpropagate at full amplitude up to the tuft
2 Yes Distal apical dendrite I N
3 Yes Middle apical dendrite I Na,t Dendritic patch recordings showed an even density of Na channels (120pS um-2) up to 350 um from the soma along the primary dendrite to the origin of the glomerular tuft
4 Yes Axon terminal I N inferred
5 Yes Soma I K Using whole-cell recordings, the kinetic properties of this current have been investigated in neurones from neonatal rats, which were retrogradely labelled and identified after enzymatic dissociation
6 Yes Distal apical dendrite I A
7 Yes Middle apical dendrite I A
8 Yes Distal apical dendrite I A report the presence and function of Ih.
9 Yes Middle apical dendrite I h report the presence and function of Ih.
10 Yes Soma I K,Ca Unpublished data by Chen and Shepherd have revealed a long lasting after hyperpolarization following a train of action potentials. Using whole-cell recordings, the kinetic properties of this current have been investigated in neurones from neonatal rats, which were retrogradely labelled and identified after enzymatic dissociation
11 Yes Proximal apical dendrite I N
12 Yes Distal basal dendrite I Na,t By combining intracellular recordings and two-photon microscopy imaging of [Ca]i it was shown that AP propagate at full amplitude up to the most distal branches
13 Yes Distal basal dendrite I N Implied by data on more proximal dendritic regions; still to be tested
14 Yes Middle basal dendrite I A By using dendritic recordings and calcium transients in rats it was shown that this current may control AP propagation in lateral dendrites
15 Yes Proximal basal dendrite I A By using dendritic recordings and calcium transients in rats it was shown that this current may control AP propagation in lateral dendrites
16 Yes Soma I K,leak Assumed.
17 Yes Soma I p,q
18 Yes Soma I L high threshold
19 Yes Soma I T low threshold
20 Yes Soma I A Using whole-cell recordings, the kinetic properties of this current have been investigated in neurones from neonatal rats, which were retrogradely labelled and identified after enzymatic dissociation
21 Yes Middle apical dendrite I N
22 Yes Proximal apical dendrite I Na,t Dendritic patch recordings showed an even density of Na channels (120pS um-2) up to 350 um from the soma along the primary dendrite to the origin of the glomerular tuft
23 Yes Middle basal dendrite I N
24 Yes Middle basal dendrite I Na,t By combining intracellular recordings and two-photon microscopy imaging of [Ca]i it was shown that AP propagate at full amplitude up to the most distal branches
25 Yes Proximal basal dendrite I N
26 Yes Proximal basal dendrite I Na,t By combining intracellular recordings and two-photon microscopy imaging of [Ca]i it was shown that AP propagate at full amplitude up to the most distal branches
27 Yes Axon hillock I Na,t Estimated: HH model slightly modified from Traub, 1982
28 Yes Axon hillock I K
29 Yes Axon fiber I Na,t Conduction of the action potential suggests there must be some Na channels there.
30 Yes Proximal apical dendrite I A
31 Yes Soma I h report the presence and function of Ih.
32 Yes Distal basal dendrite I A By using dendritic recordings and calcium transients in rats it was shown that this current may control AP propagation in lateral dendrites
 Neuronal Transmitters (8)
  
SN Property present CF-Compartment transmitter Connect Note Publication facts
1 Yes Soma Glutamate see also Felix and MacLennan, 1971).
2 Yes Distal apical dendrite Glutamate Implied by Glu released by other compartments of the mitral cell (Dale's law). Target (destination) is presumably PG cell dendrites in the glomerulus
3 Yes Middle apical dendrite Glutamate
4 Yes Proximal apical dendrite Glutamate
5 Yes Distal basal dendrite Glutamate
6 Yes Middle basal dendrite Glutamate
7 Yes Proximal basal dendrite Glutamate
8 Yes Axon terminal Glutamate
Other categories referring to Olfactory bulb main tufted middle GLU cell
Computational model.Model Neurons   (2)
2 Objects Relationship (edge).Object Two (target)   (1)
Cell Type.NeuronDB Neuron   (1)
Neuronal Structure.Neurons   (1)
Revisions: 4
Last Time: 2/18/2015 4:40:04 PM
Reviewer: Robert A McDougal
Owner: System Administrator