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Data
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A threshold equation for action potential initiation (Platkiewicz & Brette 2010)
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"We examined in models the influence of Na channel activation, inactivation, slow voltage-gated channels and synaptic conductances on spike threshold.
We propose a threshold equation which quantifies the contribution of all these mechanisms.
It provides an instantaneous time-varying value of the threshold, which applies to neurons with fluctuating inputs.
...
We find that spike threshold depends logarithmically on Na channel density, and that Na channel inactivation and K channels can dynamically modulate it in an adaptive way: the threshold increases with membrane potential and after every action potential.
" See paper for more.
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Neuron or other electrically excitable cell Show
Other
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tom.morse@yale.edu
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