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Data
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Learning intrinsic excitability in Medium Spiny Neurons (Scheler 2014)
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"We present an unsupervised, local activation-dependent learning rule for intrinsic plasticity (IP) which affects the composition of ion channel conductances for single neurons in a use-dependent way.
We use a single-compartment conductance-based model for medium spiny striatal neurons in order to show the effects of parameterization of individual ion channels on the neuronal membrane potential-curent relationship (activation function).
We show that parameter changes within the physiological ranges are sufficient to create an ensemble of neurons with significantly different activation functions.
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Neostriatum medium spiny direct pathway GABA cell Show
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Neostriatum medium spiny indirect pathway GABA cell Show
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Neuron or other electrically excitable cell Show
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Schumann, Johann [johann.schumann at gmail.com] Show
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gscheler@gmail.com
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Medium Spiny neuron
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Intrinsic Excitability
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Schumann, Johann johann.schumann@gmail.com
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doi: 10.12688/f1000research.2-88.v2
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