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Data
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Information transmission in cerebellar granule cell models (Rossert et al. 2014)
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" ... In this modeling study we analyse how electrophysiological
granule cell properties and spike sampling influence information coded
by firing rate modulation, assuming no signal-related, i.e.,
uncorrelated inhibitory feedback (open-loop mode). A detailed
one-compartment granule cell model was excited in simulation by either
direct current or mossy-fiber synaptic inputs. Vestibular signals were
represented as tonic inputs to the flocculus modulated at frequencies
up to 20 Hz (approximate upper frequency limit of vestibular-ocular
reflex, VOR). Model outputs were assessed using estimates of both the
transfer function, and the fidelity of input-signal reconstruction
measured as variance-accounted-for. The detailed granule cell model
with realistic mossy-fiber synaptic inputs could transmit infoarmation
faithfully and linearly in the frequency range of the
vestibular-ocular reflex. ... "
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Cerebellum interneuron granule GLU cell Show
Other
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Rössert C, Solinas S, D'Angelo E, Dean P, Porrill J (2014) Show
Other
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Solinas, Sergio [solinas at unipv.it] Show
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Roessert, Christian [christian.a at roessert.de] Show
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christian.a@roessert.de
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