BrainPharm: Computational model - Cerebellar purkinje cell: K and Ca channels regulate APs (Miyasho et al 2001)

Computational model

Data

Name

Cerebellar purkinje cell: K and Ca channels regulate APs (Miyasho et al 2001)

Submitter name

Pipeline ID

Model File

prknj_r1 [?]

Notes

We adopted De Schutter and Bower's model as the starting point, then modified the descriptions of several ion channels, such as the P-type Ca channel and the delayed rectifier K channel, and added class-E Ca channels and D-type K channels to the model. Our new model reproduces most of our experimental results and supports the conclusions of our experimental study that class-E Ca channels and D-type K channels are present and functioning in the dendrites of Purkinje neurons.

Model Neurons

Cerebellum Purkinje GABA cell Show Other

More Cells

Model Currents

I Na,p Show Other
I Na,t Show Other
I T low threshold Show Other
I A Show Other
I K Show Other
I M Show Other
I K,Ca Show Other
I Sodium Show Other
I Calcium Show Other
I Potassium Show Other
I A, slow Show Other
I_KD Show Other

Model Receptors

Model Type

Neuron or other electrically excitable cell Show Other

Model Concept

Action Potential Initiation Show Other
Activity Patterns Show Other
Dendritic Action Potentials Show Other
Bursting Show Other
Active Dendrites Show Other
Influence of Dendritic Geometry Show Other
Detailed Neuronal Models Show Other
Action Potentials Show Other
Calcium dynamics Show Other

Simulator software

NEURON Show Other

Model papers

Miyasho T, Takagi H, Suzuki H, Watanabe S, Inoue M, Kudo Y, Miyakawa H (2001) Show Other

Gene

hg folder name (applicable when in ModelDB hg)

prknj

Region Organism

Model ID Number

Gap Junctions

Implemented by

Miyakawa, H [Miyakawa at ls.toyaku.ac.jp] Show Other

Public Submitter Email Address

Other Neuron

Model Neurotransmitters

Other Receptor

Other Current

Other Neurotransmitter

Other Model Type

Other Concept

Other Simulator

Other Implementer

Alternative Version

Citation

Default File Notes

Other Gene

Simulation Platform ID

197

Has Model View

True

Component

RAM

Hide Auto-launch button

False

Run Protocols

17664 Show Other

ICG Channel Details

Species

Other categories referring to Cerebellar purkinje cell: K and Ca channels regulate APs (Miyasho et al 2001)

Revisions:	14
Last Time:	12/10/2013 3:37:09 PM
Reviewer:	Tom Morse - MoldelDB admin
Owner:	Tom Morse - MoldelDB admin