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Data
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Model of eupnea and sigh generation in respiratory network (Toporikova et al 2015)
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Based on recent in vitro data obtained in the mouse embryo, we have built a computational model consisting of two compartments, interconnected through appropriate synapses. One compartment generates sighs and the other produces eupneic bursts. The model reproduces basic features of simultaneous sigh and eupnea generation (two types of bursts differing in terms of
shape, amplitude, and frequency of occurrence) and mimics the effect of blocking glycinergic synapses
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Toporikova N, Chevalier M, Thoby-Brisson M (2015) Show
Other
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pre-Bötzinger complex
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toporikovan@wlu.edu
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Toporikova, N., Chevalier, M., & Thoby-Brisson, M. (2015).Sigh and Eupnea Rhythmogenesis Involve Distinct Interconnected Subpopulations: A Combined
Computational and Experimental Study. E. Journal of Neuroscience.
DOI:http://dx.doi.org/10.1523/ENEURO.0074-14.2015
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