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Efficient Method for Computing Synaptic Conductance (Destexhe et al 1994)
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A simple model of transmitter release is used to solve first order kinetic equations of neurotransmiter/receptor binding. This method is applied to a glutamate and gabaa receptor. See reference for more details. The method is extended to more complex kinetic schemes in a seperate paper (Destexhe et al J Comp Neuro 1:195-231, 1994). Application to AMPA, NMDA, GABAA, and GABAB receptors is given in a book chapter (Destexhe et al In: The Neurobiology of Computation, Edited by Bower, J., Kluwer Academic Press, Norwell MA, 1995, pp. 9-14.) More information and papers at
http://cns.iaf.cnrs-gif.fr/Main.html
and through email: Destexhe@iaf.cnrs-gif.fr
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Destexhe A, Mainen Z, Sejnowski TJ (1994) Show
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Destexhe, Alain [Destexhe at iaf.cnrs-gif.fr] Show
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Mainen, Zach [Mainen at cshl.edu] Show
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231
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