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Phase plane reveals two slow variables in midbrain dopamine neuron bursts (Yu and Canavier, 2015)
YuCanavier2015 [16067]
"Midbrain dopamine neurons exhibit a novel type of bursting that we call “inverted square wave bursting” when exposed to Ca2+-activated small conductance (SK) K+ channel blockers in vitro. This type of bursting has three phases: hyperpolarized silence, spiking, and depolarization block. We find that two slow variables are required for this type of bursting, and we show that the three-dimensional bifurcation diagram for inverted square wave bursting is a folded surface with upper (depolarized) and lower (hyperpolarized) branches. ..."
  • Substantia nigra pars compacta DA cell Show Other
  • Neuron or other electrically excitable cell Show Other
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Revisions: 6
Last Time: 7/31/2015 7:58:00 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin