|
|
|
Data
|
Discharge hysteresis in motoneurons (Powers & Heckman 2015)
|
|
|
|
|
|
|
"Motoneuron
activity is strongly influenced by the activation of persistent
inward currents (PICs) mediated by voltage-gated sodium and calcium
channels. ... It has recently been suggested that a number
of factors other than PIC can contribute to delta F (firing rate differences between motoneurons) values, including
mechanisms underlying spike frequency adaptation and spike threshold
accommodation. In the present study, we used a set of compartmental
models representing a sample of 20 motoneurons with a range
of thresholds to investigate how several different intrinsic motoneuron
properties can potentially contribute to variations in F values. ... Our results indicate that, although other
factors can contribute, variations in discharge hysteresis and delta F
values primarily reflect the contribution of dendritic PICs to motoneuron
activation.
|
-
Spinal cord lumbar motor neuron alpha ACh cell Show
Other
|
|
|
|
|
|
|
-
Neuron or other electrically excitable cell Show
Other
|
|
|
|
|
|
|
|
|
183949
|
|
|
|
|
|
|
-
Powers, Randy [rkpowers at u.washington.edu] Show
Other
|
tom.morse@yale.edu
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
