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NMDA spikes in basal dendrites of L5 pyramidal neurons (Polsky et al. 2009)
"... In apical dendrites of neocortical pyramidal neurons, calcium spikes are known to contribute to burst generation, but a comparable understanding of basal dendritic mechanisms is lacking. Here we show that NMDA spikes in basal dendrites mediate both detection and generation of bursts through a postsynaptic mechanism. High-frequency inputs to basal dendrites markedly facilitated NMDA spike initiation compared with low-frequency activation or single inputs. ..."
  • Neocortex L5/6 pyramidal GLU cell Show Other
  • Neuron or other electrically excitable cell Show Other
  • Polsky A, Mel B, Schiller J (2009) Show Other
  • Polsky, Alon [alonpol at tx.technion.ac.il] Show Other
tom.morse@yale.edu
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Other categories referring to NMDA spikes in basal dendrites of L5 pyramidal neurons (Polsky et al. 2009)
Revisions: 2
Last Time: 9/9/2015 6:02:08 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin