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Data
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NMDA spikes in basal dendrites of L5 pyramidal neurons (Polsky et al. 2009)
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"...
In apical
dendrites of neocortical pyramidal neurons, calcium spikes are known
to contribute to burst generation, but a comparable understanding of
basal dendritic mechanisms is lacking. Here we show that NMDA spikes
in basal dendrites mediate both detection and generation of bursts
through a postsynaptic mechanism.
High-frequency inputs to basal
dendrites markedly facilitated NMDA spike initiation compared with
low-frequency activation or single inputs.
..."
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Neuron or other electrically excitable cell Show
Other
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Polsky A, Mel B, Schiller J (2009) Show
Other
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Polsky, Alon [alonpol at tx.technion.ac.il] Show
Other
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tom.morse@yale.edu
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