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Data
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Ca+/HCN channel-dependent persistent activity in multiscale model of neocortex (Neymotin et al 2016)
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"Neuronal persistent activity has been primarily assessed in terms of electrical mechanisms, without attention to the complex array of molecular events that also control cell excitability. We developed a multiscale neocortical model proceeding from the molecular to the network level to assess the contributions of calcium regulation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in providing additional and complementary support of continuing activation in the network. ..."
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Neocortex L5/6 pyramidal GLU cell Show
Other
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Neocortex L2/3 pyramidal GLU cell Show
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Neocortex V1 interneuron basket PV GABA cell Show
Other
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Neocortex fast spiking (FS) interneuron Show
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Neocortex spiking regular (RS) neuron Show
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Neocortex spiking low threshold (LTS) neuron Show
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Neocortex layer 2-3 interneuron Show
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Neocortex layer 5 interneuron Show
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Neocortex layer 6a interneuron Show
Other
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Neymotin SA, McDougal RA, Bulanova AS, Zeki M, Lakatos P, Terman D, Hines ML, Lytton WW (2016) Show
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CaHDemo
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Neymotin, Sam [Samuel.Neymotin at nki.rfmh.org] Show
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McDougal, Robert [robert.mcdougal at yale.edu] Show
Other
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Anna Bulanova
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