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CA3 Network Model of Epileptic Activity (Sanjay et. al, 2015)
M Sanjay
SanjayEtAl2015 [790509]
This computational study investigates how a CA3 neuronal network consisting of pyramidal cells, basket cells and OLM interneurons becomes epileptic when dendritic inhibition to pyramidal cells is impaired due to the dysfunction of OLM interneurons. After standardizing the baseline activity (theta-modulated gamma oscillations), systematic changes are made in the connectivities between the neurons, as a result of step-wise impairment of dendritic inhibition.
  • Hippocampus CA3 pyramidal GLU cell Show Other
  • Hippocampus CA3 interneuron basket GABA cell Show Other
  • Hippocampus CA3 stratum oriens lacunosum-moleculare interneuron Show Other
  • Sanjay M, Neymotin SA, Krothapalli SB (2015) Show Other
  • Neymotin, Sam [Samuel.Neymotin at nki.rfmh.org] Show Other
  • Sanjay, M [msanjaycmc at gmail.com] Show Other
msanjaycmc@gmail.com
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Revisions: 9
Last Time: 3/18/2017 10:18:14 AM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin