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A mathematical model of evoked calcium dynamics in astrocytes (Handy et al 2017)
HandyEtAl2017 [260742]
" ...Here we present a qualitative analysis of a recent mathematical model of astrocyte calcium responses. We show how the major response types are generated in the model as a result of the underlying bifurcation structure. By varying key channel parameters, mimicking blockers used by experimentalists, we manipulate this underlying bifurcation structure and predict how the distributions of responses can change. We find that store-operated calcium channels, plasma membrane bound channels with little activity during calcium transients, have a surprisingly strong effect, underscoring the importance of considering these channels in both experiments and mathematical settings. ..."
  • Handy G, Taheri M, White JA, Borisyuk A (2017) Show Other
I_SOC
Astrocytes
XPP
Gregory Handy, Marsa Taheri
False
False
Other categories referring to A mathematical model of evoked calcium dynamics in astrocytes (Handy et al 2017)
Revisions: 17
Last Time: 3/31/2017 12:26:31 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin