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Data
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Modeling epileptic seizure induced by depolarization block (Kim & Dykamp 2017)
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Christopher Kim
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"The inhibitory restraint necessary to suppress
aberrant activity can fail when inhibitory neurons cease to
generate action potentials as they enter depolarization block.
We investigate possible bifurcation structures that arise at
the onset of seizure-like activity resulting from depolarization
block in inhibitory neurons. Networks of conductance based
excitatory and inhibitory neurons are simulated to
characterize different types of transitions to the seizure
state, and a mean field model is developed to verify the generality
of the observed phenomena of excitatory-inhibitory
dynamics. ..."
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Kim, Christopher M [christopher.kim3 at nih.gov] Show
Other
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c.kim@bcf.uni-freiburg.de
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