BrainPharm: Computational model - Model of Type 3 firing in neurons (Clay et al 2008)

Computational model

Data

Name

Model of Type 3 firing in neurons (Clay et al 2008)

Submitter name

Pipeline ID

Model File

ClayEtAl2008 [369660]

Notes

An ionic model for Type 3 firing in neurons (Clay et al 2008) Some neurons fire only once in response to a sustained depolarizing current pulse, type 3 behavior. One example, surprisingly, is the squid giant axon. The Hodgkin-Huxley (HH) model of this preparation fires repetitively for these conditions – type 2, a result that is not observed experimentally as shown in the above paper. Changing one parameter of their model of IK is sufficient to mimic the result.

Model Neurons

More Cells

Model Currents

Model Receptors

Model Type

Neuron or other electrically excitable cell Show Other

Model Concept

Simulator software

NEURON Show Other
Python Show Other

Model papers

Clay JR, Paydarfar D, Forger DB (2008) Show Other

Gene

hg folder name (applicable when in ModelDB hg)

ClayEtAl2008

Region Organism

Model ID Number

Gap Junctions

Implemented by

Ganguly, Mohit [mohit.ganguly at vanderbilt.edu] Show Other
Clay, John R Show Other

Public Submitter Email Address

Other Neuron

Model Neurotransmitters

Other Receptor

Other Current

Other Neurotransmitter

Other Model Type

Other Concept

Other Simulator

Other Implementer

Mohit Ganguly John R Clay

Alternative Version

Citation

Default File Notes

Other Gene

Simulation Platform ID

Has Model View

False

Component

RAM

Hide Auto-launch button

False

Run Protocols

ICG Channel Details

Species

Other categories referring to Model of Type 3 firing in neurons (Clay et al 2008)

Revisions:	10
Last Time:	1/30/2023 2:07:28 PM
Reviewer:	Rui Li
Owner:	Tom Morse - MoldelDB admin