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Fast AMPA receptor signaling (Geiger et al 1997)
Glutamatergic transmission at a principal neuron-interneuron synapse was investigated by dual whole-cell patch-clamp recording in rat hippocampal slices combined with morphological analysis and modeling. Simulations based on a compartmental model of the interneuron indicated that the rapid postsynaptic conductance change determines the shape and the somatodendritic integration of EPSPs, thus enabling interneurons to detect synchronous principal neuron activity.
  • Geiger JR, Lübke J, Roth A, Frotscher M, Jonas P (1997) Show Other
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Revisions: 13
Last Time: 2/14/2014 3:30:10 PM
Reviewer: Robert A McDougal
Owner: Tom Morse - MoldelDB admin