Computational model
Cerebellum granule cell FHF (Dover et al. 2016)
GrC_FHF_ModelDB [105759]
"Neurons in vertebrate central nervous systems initiate and conduct sodium action potentials in distinct subcellular compartments that differ architecturally and electrically. Here, we report several unanticipated passive and active properties of the cerebellar granule cell's unmyelinated axon. Whereas spike initiation at the axon initial segment relies on sodium channel (Nav)-associated fibroblast growth factor homologous factor (FHF) proteins to delay Nav inactivation, distal axonal Navs show little FHF association or FHF requirement for high-frequency transmission, velocity and waveforms of conducting action potentials. ...'
  • Cerebellum interneuron granule GLU cell Show Other
  • Dover K, Marra C, Solinas S, Popovic M, Subramaniyam S, Zecevic D, D'Angelo E, Goldfarb M (2016) Show Other
  • Solinas, Sergio [solinas at] Show Other
  • Subramaniyam, Sathyaa [sakthisathyaa at] Show Other
  • D'Angelo, Egidio [dangelo at] Show Other
  • Goldfarb, Mitchell goldfarb at] Show Other
Goldfarb, Mitchell Subramaniyam, Sathyaa
Other categories referring to Cerebellum granule cell FHF (Dover et al. 2016)
Revisions: 16
Last Time: 1/27/2023 1:13:25 PM
Reviewer: Rui Li
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