Computational model
In vivo imaging of dentate gyrus mossy cells in behaving mice (Danielson et al 2017)
Spyridon Chavlis
Danielson2017_r2 [534470]
Mossy cells in the hilus of the dentate gyrus constitute a major excitatory principal cell type in the mammalian hippocampus, however, it remains unknown how these cells behave in vivo. Here, we have used two-photon Ca2+ imaging to monitor the activity of mossy cells in awake, behaving mice. We find that mossy cells are significantly more active than dentate granule cells in vivo, exhibit significant spatial tuning during head-fixed spatial navigation, and undergo robust remapping of their spatial representations in response to contextual manipulation. Our results provide the first characterization of mossy cells in the behaving animal and demonstrate their active participation in spatial coding and contextual representation.
  • Dentate gyrus basket cell Show Other
  • Dentate gyrus hilar cell Show Other
  • Dentate gyrus mossy cell Show Other
  • Abstract integrate-and-fire adaptive exponential (AdEx) neuron Show Other
  • Danielson NB, Turi GF, Ladow M, Chavlis S, Petrantonakis PC, Poirazi P, Losonczy A (2017) Show Other
  • Chavlis, Spyridon [schavlis at] Show Other
  • Petrantonakis, Panagiotis C. Show Other
  • Poirazi, Panayiota [poirazi at] Show Other
Point Neuronal Network
Panagiotis Petrantonakis Panayiota Poirazi
Other categories referring to In vivo imaging of dentate gyrus mossy cells in behaving mice (Danielson et al 2017)
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Last Time: 7/28/2017 1:53:32 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin