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Data
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Regulation of motoneuron excitability by KCNQ/Kv7 modulators (Lombardo & Harrington 2016)
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Joseph Lombardo
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" ... Computer simulations confirmed that pharmacological enhancement
of KCNQ/Kv7 channel (M current) activity decreases excitability and
also suggested that the effects of inhibition of KCNQ/Kv7 channels on
the excitability of spinal MNs do not depend on a direct effect in
these neurons but likely on spinal cord synaptic partners. These
results indicate that KCNQ/Kv7 channels have a fundamental role in the
modulation of the excitability of spinal MNs acting both in these
neurons and in their local presynaptic partners. ..."
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Spinal cord lumbar motor neuron alpha ACh cell Show
Other
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Neuron or other electrically excitable cell Show
Other
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217882
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Lombardo, Joseph [josslomb at gmail.com] Show
Other
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josslomb@gmail.com
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