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Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Tom Morse
AlturkiEtAl2016 [505689]
" ... We hypothesized that currents are grouped into distinct modules that shape specific neuronal characteristics or signatures, such as resting potential, sub-threshold oscillations, and spiking waveforms, for several classes of neurons. For such a grouping to occur, the currents within one module should have minimal functional interference with currents belonging to other modules. This condition is satisfied if the gating functions of currents in the same module are grouped together on the voltage axis; in contrast, such functions are segregated along the voltage axis for currents belonging to different modules. We tested this hypothesis using four published example case models and found it to be valid for these classes of neurons. ..."
  • Abstract single compartment conductance based cell Show Other
  • Neuron or other electrically excitable cell Show Other
  • Alturki A, Feng F, Nair A, Guntu V, Nair SS (2016) Show Other
tom.morse@yale.edu
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Revisions: 9
Last Time: 10/17/2018 4:20:09 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin