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Sloppy morphological tuning in identified neurons of the crustacean STG (Otopalik et al 2017)
tom.morse@yale.edu
" ...Theoretical studies suggest that morphology is tightly tuned to minimize wiring and conduction delay of synaptic events. We utilize high-resolution confocal microscopy and custom computational tools to characterize the morphologies of four neuron types in the stomatogastric ganglion (STG) of the crab Cancer borealis. Macroscopic branching patterns and fine cable properties are variable within and across neuron types. We compare these neuronal structures to synthetic minimal spanning neurite trees constrained by a wiring cost equation and find that STG neurons do not adhere to prevailing hypotheses regarding wiring optimization principles. In this highly-modulated and oscillating circuit, neuronal structures appear to be governed by a space-filling mechanism that outweighs the cost of inefficient wiring."
  • Stomatogastric Ganglion (STG) Lateral Gastric (LG) cell Show Other
  • Stomatogastric Ganglion (STG) Lateral Pyloric (LP) cell Show Other
  • Stomatogastric ganglion (STG) pyloric dilator (PD) neuron Show Other
  • Stomatogastric Ganglion (STG) Gastric Mill (GM) cell Show Other
  • Neuron or other electrically excitable cell Show Other
  • Otopalik AG, Goeritz ML, Sutton AC, Brookings T, Guerini C, Marder E (2017) Show Other
tom.morse@yale.edu
pyloric dilator (PD, gastric mill GM neurons
False
False
Other categories referring to Sloppy morphological tuning in identified neurons of the crustacean STG (Otopalik et al 2017)
Revisions: 3
Last Time: 2/15/2017 11:38:56 AM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin