Computational model
A detailed Purkinje cell model (Masoli et al 2015)
Stefano Masoli
The Purkinje cell is one of the most complex type of neuron in the central nervous system and is well known for its massive dendritic tree. The initiation of the action potential was theorized to be due to the high calcium channels presence in the dendritic tree but, in the last years, this idea was revised. In fact, the Axon Initial Segment, the first section of the axon was seen to be critical for the spontaneous generation of action potentials. The model reproduces the behaviours linked to the presence of this fundamental sections and the interplay with the other parts of the neuron.
  • Masoli S, Solinas S, D'Angelo E (2015) Show Other
  • Masoli, Stefano [stefano.masoli at] Show Other
  • Solinas, Sergio [solinas at] Show Other
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