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Data
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Model for concentration invariant odor coding based on primacy hypothesis (Wilson et al 2017)
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Alexei Koulakov
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"... Here we
propose that, in olfaction, a small and relatively stable set
comprised of the earliest activated receptors forms a code for
concentration-invariant odor identity. One prediction of this “primacy
coding” scheme is that decisions based on odor identity can be made
solely using early odor-evoked neural activity. Using an optogenetic
masking paradigm, we define the sensory integration time necessary for
odor identification and demonstrate that animals can use information
occurring <100ms after inhalation onset to identify odors.
... We
propose a computational model demonstrating how such a code can be
read by neural circuits of the olfactory system."
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Olfactory bulb main mitral GLU cell Show
Other
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Neuron or other electrically excitable cell Show
Other
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Wilson CD, Serrano GO, Koulakov AA, Rinberg D (2017) Show
Other
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Koulakov, Alexei [akula at cshl.edu] Show
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akula@cshl.edu
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piriform cortex neuron
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AMPA
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concentration invariant o
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Koulakov, Alexei (akula@cshl.edu)
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