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Data
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Behavioral time scale synaptic plasticity underlies CA1 place fields (Bittner et al. 2017)
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" ... Place fields could be produced
in vivo in a single trial by potentiation of input that arrived seconds before and after complex
spiking.The potentiated synaptic input was not initially coincident with action potentials or
depolarization.This rule, named behavioral timescale synaptic plasticity, abruptly modifies inputs
that were neither causal nor close in time to postsynaptic activation. ...", " ... To determine if the above plasticity rule could
be observed under more realistic model conditions,
we constructed and optimized a biophysically
detailed model and attempted to fully account
for the experimental data. ... "
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Hippocampus CA1 pyramidal GLU cell Show
Other
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Bittner KC, Milstein AD, Grienberger C, Romani S, Magee JC (2017) Show
Other
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Milstein, Aaron D. [aaronmil at stanford.edu] Show
Other
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tom.morse@yale.edu
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A. D. Milstein
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