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A unified thalamic model of multiple distinct oscillations (Li, Henriquez and Fröhlich 2017)
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We present a unified model of the thalamus that is capable of independently generating multiple distinct oscillations (delta, spindle, alpha and gamma oscillations) under different levels of acetylcholine (ACh) and norepinephrine (NE) modulation corresponding to different physiological conditions (deep sleep, light sleep, relaxed wakefulness and attention). The model also shows that entrainment of thalamic oscillations is state-dependent.
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Thalamus geniculate nucleus/lateral principal GLU cell Show
Other
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Thalamus reticular nucleus GABA cell Show
Other
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Thalamus lateral geniculate nucleus interneuron Show
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Li G, Henriquez C, Fröhlich F (2017) Show
Other
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ThalamicOSC
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Li, Guoshi [guoshi_li at med.unc.edu] Show
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guoshi_li@med.unc.edu
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Guoshi Li, Craig Henriquez and Flavio Fröhlich (2017) Unified Thalamic Model Generates Multiple Distinct Oscillations with State-dependent Entrainment by Stimulation. PLOS Computational Biology (In press).
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