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A model for recurrent spreading depolarizations (Conte et al. 2017)
David Hillel Terman
terman-ModelDB [347582]
A detailed biophysical model for a neuron/astrocyte network is developed in order to explore mechanisms responsible for cortical spreading depolarizations. This includes a model for the Na+-glutamate transporter, which allows for a detailed description of reverse glutamate uptake. In particular, we consider the specific roles of elevated extracellular glutamate and K+ in the initiation, propagation and recurrence of spreading depolarizations.
  • Conte C, Lee R, Sarkar M, Terman D (2018) Show Other
  • Terman, David [terman at math.ohio-state.edu] Show Other
terman.1@osu.edu
Na+-glutamate transporter
Spreading depolarization
Journal of Computational Neuroscience https://doi.org/10.1007/s10827-017-0675-3
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Revisions: 6
Last Time: 12/14/2017 6:58:42 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin