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Data
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2 Distinct Classes of L2 and L3 Pyramidal Neurons in Human Temporal Cortex (Deitcher et al 2017)
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Pipeline user
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"There have been few quantitative characterizations of the
morphological, biophysical, and cable properties of neurons in the
human neocortex. We employed feature-based statistical methods on a
rare data set of 60 3D reconstructed pyramidal neurons from L2 and L3
in the human temporal cortex (HL2/L3 PCs) removed after brain
surgery. Of these cells, 25 neurons were also characterized
physiologically. Thirty-two morphological features were analyzed
(e.g., dendritic surface area, 36 333 ± 18 157 µm2; number of basal
trees, 5.55 ± 1.47; dendritic diameter, 0.76 ± 0.28 µm).
...
A novel descriptor for apical dendritic
topology yielded 2 distinct classes, termed hereby as “slim-tufted”
and “profuse-tufted” HL2/L3 PCs; the latter class tends to fire at
higher rates. Thus, our morpho-electrotonic analysis shows 2 distinct
classes of HL2/L3 PCs."
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Neuron or other electrically excitable cell Show
Other
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Deitcher Y, Eyal G, Kanari L, Verhoog MB, Atenekeng Kahou GA, Mansvelder HD, de Kock CPJ, Segev I (2017) Show
Other
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DeitcherEtAl2017
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Eyal, Guy [guy.eyal at mail.huji.ac.il] Show
Other
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Deitcher, Yair [yair.deitcher at mail.huji.ac.il] Show
Other
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tom.morse@yale.edu
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https://academic.oup.com/cercor/article/doi/10.1093/cercor/bhx226/4159219/Comprehensive-Morpho-Electrotonic-Analysis-Shows-2
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