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MDD: the role of glutamate dysfunction on Cingulo-Frontal NN dynamics (Ramirez-Mahaluf et al 2017)
Tom Morse - MoldelDB admin
" ...Currently, no mechanistic framework describes how network dynamics, glutamate, and serotonin interact to explain MDD symptoms and treatments. Here, we built a biophysical computational model of 2 areas (vACC and dlPFC) that can switch between emotional and cognitive processing. (Major Depression Disease) MDD networks were simulated by slowing glutamate decay in vACC and demonstrated sustained vACC activation. ..."
  • Abstract integrate-and-fire leaky neuron Show Other
  • Ramirez-Mahaluf JP, Roxin A, Mayberg HS, Compte A (2017) Show Other
  • Ramirez-Mahaluf, Juan P [jpramirezmahaluf at gmail.com] Show Other
tom.morse@yale.edu
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Other categories referring to MDD: the role of glutamate dysfunction on Cingulo-Frontal NN dynamics (Ramirez-Mahaluf et al 2017)
Revisions: 7
Last Time: 11/9/2018 2:55:17 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin