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Data
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Contribution of the axon initial segment to APs recorded extracellularly (Telenczuk et al 2018)
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"... It
was recently proposed that at onset of an (Action Potential) AP the soma and the (Axon Initial Segment) AIS form
a dipole.
We study the extracellular signature (the extracellular
action potential, EAP) generated by such a dipole.
First, we
demonstrate the formation of the dipole and its extracellular
signature in detailed morphological models of a reconstructed
pyramidal neuron.
Then, we study the EAP waveform and its spatial
dependence in models with axonal AP initiation and contrast it with
the EAP obtained in models with somatic AP initiation.
We show that in
the models with axonal AP initiation the dipole forms between
somatodendritic compartments and the AIS, and not between soma and
dendrites as in the classical models.
..."
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Telenczuk M, Brette R, Destexhe A, Telenczuk B (2018) Show
Other
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Telenczuk, Maria [mtelenczuk at unic.cnrs-gif.fr] Show
Other
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Telenczuk, Bartosz [bartosz.telenczuk at inaf.cnrs-gif.fr] Show
Other
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tom.morse@yale.edu
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Telenczuk et al 2018
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