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Cells were voltage-clamped using a single microelectrode, at 23-30 degrees C. M-current resembled that of sympathetic ganglion cells. It was abolished by addition of carbachol, muscarine or bethanechol, as well as by 1 mM barium. It was suggested that activation of cholinergic septal inputs to the hippocampus facilitates repetitive firing of pyramidal cells by turning off the M-conductance, without much change in the resting potential of the cell
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guinea pig
Other categories referring to Cells were voltage-clamped using a single microelectrode, at 23-30 degrees C. M-current resembled that of sympathetic ganglion cells. It was abolished by addition of carbachol, muscarine or bethanechol, as well as by 1 mM barium. It was suggested that activation of cholinergic septal inputs to the hippocampus facilitates repetitive firing of pyramidal cells by turning off the M-conductance, without much change in the resting potential of the cell
Neuronal Currents.Publication facts   (1)
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