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Response to correlated synaptic input for HH/IF point neuron vs with dendrite (Górski et al 2018)
Tomasz Górski
gorski2018 [14603]
" ... Here, we study computational models of neurons to investigate the functional effects of dendritic spikes. In agreement with previous studies, we found that point neurons or neurons with passive dendrites increase their somatic firing rate in response to the correlation of synaptic bombardment for a wide range of input conditions, i.e. input firing rates, synaptic conductances, or refractory periods. However, neurons with active dendrites show the opposite behavior: for a wide range of conditions the firing rate decreases as a function of correlation. We found this property in three types of models of dendritic excitability: a Hodgkin-Huxley model of dendritic spikes, a model with integrate and fire dendrites, and a discrete-state dendritic model. We conclude that fast dendritic spikes confer much broader computational properties to neurons, sometimes opposite to that of point neurons."
  • Neuron or other electrically excitable cell Show Other
  • Górski T, Veltz R, Galtier M, Fragnaud H, Goldman JS, Telenczuk B, Destexhe A (2018) Show Other
  • Górski, Tomasz [gorski at inaf.cnrs-gif.fr] Show Other
tomasz.gorski.14@gmail.com
https://www.biorxiv.org/content/early/2017/05/14/137984
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Revisions: 19
Last Time: 12/14/2018 12:21:32 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin