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Compartmental differences in cAMP signaling pathways in hippocam. CA1 pyr. cells (Luczak et al 2017)
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Kim Blackwell
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Model of cAMP signaling pathways in hippocampal CA1 pyramidal neurons investigate mechanisms underlying the experimentally observed difference in cAMP and PKA FRET between proximal and distal dendrites. Simulations show that compartmental difference in PKA activity required enrichment of protein phosphatase in small compartments; neither reduced PKA subunits nor increased PKA substrates were sufficient.
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Hippocampus CA1 pyramidal GLU cell Show
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Luczak V, Blackwell KT, Abel T, Girault JA, Gervasi N (2017) Show
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LuczakEtAl2017
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Blackwell, Avrama [avrama at gmu.edu] Show
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kblackw1@gmu.edu
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NeuroRD-3.0.0.8
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