Computational model
Quantitative model of sleep-wake dynamics (Phillips & Robinson 2007)
Tom Morse - MoldelDB admin [119488]
"A quantitative, physiology-based model of the ascending arousal system is developed, using continuum neuronal population modeling, which involves averaging properties such as firing rates across neurons in each population. The model includes the ventrolateral preoptic area (VLPO), where circadian and homeostatic drives enter the system, the monoaminergic and cholinergic nuclei of the ascending arousal system, and their interconnections. The human sleep-wake cycle is governed by the activities of these nuclei, which modulate the behavioral state of the brain via diffuse neuromodulatory projections. ... The model behavior is robust across the constrained parameter ranges, but with sufficient flexibility to describe a wide range of observed phenomena. "
Phillips Johnson 2007
Other categories referring to Quantitative model of sleep-wake dynamics (Phillips & Robinson 2007)
Revisions: 2
Last Time: 12/4/2018 2:41:31 PM
Reviewer: Tom Morse - MoldelDB admin
Owner: Tom Morse - MoldelDB admin